1,2,3-Triazole: Unique Ligand in Promoting Iron-Catalyzed Propargyl Alcohol Dehydration

详细信息    查看全文

• 作者：Wuming Yan ; Xiaohan Ye ; Novruz G. Akhmedov ; Jeffrey L. Petersen ; Xiaodong Shi
• 刊名：Organic Letters
• 出版年：2012
• 出版时间：May 4, 2012
• 年：2012
• 卷：14
• 期：9
• 页码：2358-2361
• 全文大小：301K
• 年卷期：v.14,no.9(May 4, 2012)
• ISSN：1523-7052

文摘

A 1,2,3-traizole-promoted iron(III)-catalyzed propargyl alcohol dehydration was developed for the synthesis of conjugated enynes. The desired conjugated enynes were prepared in good to excellent yields (up to 95%) with a large substrate scope and excellent stereoselectivity (only Z-isomers).