Design, Multicomponent Synthesis, and Bioactivities of Novel Neonicotinoid Analogues with 1,4-Dihydropyridine Scaffold

详细信息    查看全文

• 作者：Wenwen Zhang ; Xiaobao Yang ; Weidong Chen ; Xiaoyong Xu ; Lu Li ; Hongbin Zhai ; Zhong Li
• 刊名：Journal of Agricultural and Food Chemistry
• 出版年：2010
• 出版时间：March 10, 2010
• 年：2010
• 卷：58
• 期：5
• 页码：2741-2745
• 全文大小：718K
• 年卷期：v.58,no.5(March 10, 2010)
• ISSN：1520-5118

文摘

Novel neonicotinoid analogues bearing a 1,4-dihydropridine scaffold were designed and synthesized by multicomponent reactions (MCRs) to enhance π−π stacking. The synthesized compounds were identified by ¹H NMR, ¹³C NMR, high-resolution mass spectroscopy, and elemental analysis. Bioassay tests showed that some of them exhibited high insecticidal activities against pea aphid (Aphis craccivora).