Tissue Deposition and Residue Depletion in Laying Hens Exposed to Melamine-Contaminated Diets

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• 作者：Xue Bai ; Fan Bai ; Keying Zhang ; Xiaowen Lv ; Yuchang Qin ; Yun Li ; Shiping Bai ; Shunquan Lin
• 刊名：Journal of Agricultural and Food Chemistry
• 出版年：2010
• 出版时间：May 12, 2010
• 年：2010
• 卷：58
• 期：9
• 页码：5414-5420
• 全文大小：836K
• 年卷期：v.58,no.9(May 12, 2010)
• ISSN：1520-5118

文摘

To investigate the deposition and elimination of melamine in hen eggs and tissues, 72 Roman laying hens were administrated with melamine at 8.6−140.9 mg per kilogram of body weight per day for 34 days. The crystals were found in one of three kidneys of hens treated with melamine at either 62.6 or 140.9 mg/kg. Furthermore, the melamine concentrations in egg, muscle, liver, kidney, stomach, duodenum, uterus, ovary, and blood plasma were determined by high-performance liquid chromatography−ultraviolet (HPLC−UV) methods. A higher dosage of melamine in the diet corresponded to higher concentrations in tissues and eggs. The concentrations of melamine in tissues were in the following ranges (μg/g): egg, 1.1−28.7; muscle, 0.4−9.3; liver, 0.5−6.9; kidney, 1.3−21.7; stomach, 0.4−7.3; duodenum, 0.3−2.8; uterus, 0.5−6.9; ovary, 0.5−9.1; and blood plasma, 0.8−7.6. When melamine was withdrawn from the diet of hens, the melamine concentration in hen tissues fell to below 2.5 μg/g by day 10 and no residues were detected in eggs or tissues at days 7 and 20, respectively.