NaI-Mediated Acetamidosulphenylation of Alkenes with Nitriles as the Nucleophiles: A Direct Access to Acetamidosulfides

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• 作者：Yang Zheng ; Yue He ; Guangwei Rong ; Xiaolu Zhang ; Yuecheng Weng ; Kuiyong Dong ; Xinfang Xu ; Jincheng Mao
• 刊名：Organic Letters
• 出版年：2015
• 出版时间：November 6, 2015
• 年：2015
• 卷：17
• 期：21
• 页码：5444-5447
• 全文大小：393K
• ISSN：1523-7052

文摘

An example of a transition-metal-free, direct, and efficient acetamidosulphenylation reaction of alkenes using nitriles as the nucleophiles via a radical process is presented. This reaction shows a broad substrate scope and high regioselectivity and provides straightforward access to acetamidosulfide derivatives in moderate to high yields.