Cooperative Co(III)/Cu(II)-Catalyzed C–N/N–N Coupling of Imidates with Anthranils: Access to 1H-Indazoles via C–H Activation

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• 作者：Lei Li ; He Wang ; Songjie Yu ; Xifa Yang ; Xingwei Li
• 刊名：Organic Letters
• 出版年：2016
• 出版时间：August 5, 2016
• 年：2016
• 卷：18
• 期：15
• 页码：3662-3665
• 全文大小：414K
• 年卷期：0
• ISSN：1523-7052

文摘

Cooperative cobalt- and copper-catalyzed C–H activation of imidate esters and oxidative coupling with anthranils allowed efficient synthesis of 1H-indazoles in the absence of metal oxidants. The anthranil acts as a convenient aminating reagent as well as an organic oxidant in this transformation. The copper catalyst likely functions at the stage of N–N formation.