Palladium-Catalyzed Oxidative Heck Coupling Reaction for Direct Synthesis of 4-Arylcoumarins Using Coumarins and Arylboronic Acids

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• 作者：Yaming Li ; Zisong Qi ; Huifeng Wang ; Xinmei Fu ; Chunying Duan
• 刊名：The Journal of Organic Chemistry
• 出版年：2012
• 出版时间：February 17, 2012
• 年：2012
• 卷：77
• 期：4
• 页码：2053-2057
• 全文大小：304K
• 年卷期：v.77,no.4(February 17, 2012)
• ISSN：1520-6904

文摘

An efficient protocol for the direct synthesis of 4-arylcoumarins via palladium-catalyzed oxidative Heck coupling reaction of coumarins and arylboronic acids was developed. 4-Arylcoumarins were obtained in moderate to excellent yields, and the reaction also showed tolerance toward functional groups such as hydro, methoxy, diethylamino, nitro, and chloro groups.