Cobalt(III)-Catalyzed Regio- and Stereoselective α-Fluoroalkenylation of Arenes with gem-Difluorostyrenes

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• 作者：Lingheng Kong ; Xukai Zhou ; Xingwei Li
• 刊名：Organic Letters
• 出版年：2016
• 出版时间：December 16, 2016
• 年：2016
• 卷：18
• 期：24
• 页码：6320-6323
• 全文大小：426K
• ISSN：1523-7052

文摘

A cobalt(III)-catalyzed α-fluoroalkenylation of different arenes with readily available gem-difluorostyrenes has been realized under mild and redox-neutral conditions. This reaction occurs via a C–H activation pathway and offers a step-economical access to various 1,2-diaryl-substituted monofluoroalkenes in excellent Z selectivity in moderate to excellent yields.