Total Synthesis of (鈭?-Anisatin

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• 作者：Akihiro Ogura ; Kohei Yamada ; Satoshi Yokoshima ; Tohru Fukuyama
• 刊名：Organic Letters
• 出版年：2012
• 出版时间：March 16, 2012
• 年：2012
• 卷：14
• 期：6
• 页码：1632-1635
• 全文大小：302K
• 年卷期：v.14,no.6(March 16, 2012)
• ISSN：1523-7052

文摘

A novel synthetic route to (鈭?-anisatin has been developed. Our synthesis features a rhodium-catalyzed 1,4-addition of an arylboronic acid, an intramolecular Diels鈥揂lder reaction of an ortho-quinone monoketal, a stereoselective [2,3]-Wittig rearrangement, and construction of the oxabicyclo [3.3.1] skeleton via cleavage of an epoxide by a primary amide.