1,2-Alkylarylation of Styrenes with α-Carbonyl Alkyl Bromides and Indoles Using Visible-Light Catalysis

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• 作者：Meng Li ; Ji Yang ; Xuan-Hui Ouyang ; Yuan Yang ; Ming Hu ; Ren-Jie Song ; Jin-Heng Li
• 刊名：Journal of Organic Chemistry
• 出版年：2016
• 出版时间：August 19, 2016
• 年：2016
• 卷：81
• 期：16
• 页码：7148-7154
• 全文大小：425K
• 年卷期：0
• ISSN：1520-6904

文摘

A new intermolecular 1,2-alkylarylation of styrenes with α-carbonyl alkyl bromides and indoles using fac-[Ir(ppy)₃] as the photoredox catalyst has been developed. The method allows the simultaneous formation of two new carbon–carbon bonds through three component reaction, and represents a new single-electron transfer (SET) strategy for the 1,2-alkylarylation of the styrenes with broad substrate scope and excellent functional group tolerance.