Total Syntheses of (卤)-Omphadiol and (卤)-Pyxidatol C through a Cis-Fused 5,7-Carbocyclic Common Intermediate

详细信息    查看全文

• 作者：Lili Zhou ; Yanmin Yao ; Wenbo Xu ; Guangxin Liang
• 刊名：Journal of Organic Chemistry
• 出版年：2014
• 出版时间：June 6, 2014
• 年：2014
• 卷：79
• 期：11
• 页码：5345-5350
• 全文大小：306K
• 年卷期：v.79,no.11(June 6, 2014)
• ISSN：1520-6904

文摘

Total syntheses of omphadiol and pyxidatol C, two isomeric africanane sesquiterpenes sharing identical 5-7-3 tricyclic carbon skeletons yet containing distinct oxidation patterns, are reported. The trans-fused 5,7-carbocycles in the terpenoids characterized by specific oxidation patterns were derived from a readily available cis-fused 5,7-carbocyclic common intermediate.