Targeted Delivery System Based on Magnetic Mesoporous Silica Nanocomposites with Light-Controlled Release Character
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  • 作者:Yanyan Wang ; Bin Li ; Liming Zhang ; Hang Song ; Ligong Zhang
  • 刊名:ACS Applied Materials & Interfaces
  • 出版年:2013
  • 出版时间:January 9, 2013
  • 年:2013
  • 卷:5
  • 期:1
  • 页码:11-15
  • 全文大小:296K
  • 年卷期:v.5,no.1(January 9, 2013)
  • ISSN:1944-8252
文摘
We report the facile synthesis and easy operation of a smart delivery system based on core鈥搒hell structured magnetic mesoporous silica nanocomposites covalently grafted with light-responsive azobenzene derivatives, which integrates magnetic targeting and stimuli-responsive release property. Irradiation with visible light triggers the release of guest molecules loaded in the mesopores.

Keywords:

magnetic; mesoporous silica; core鈭抯hell; targeting; light-responsive; drug delivery

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