A Copper(II)-Mediated Regioselective Cyclization−Acetoxylation of 6,8-Dien-1-ones for the Synthesis of Functionalized Cyclopentanes

详细信息    查看全文

• 作者：Yazhou Wang ; Haifeng Du
• 刊名：Journal of Organic Chemistry
• 出版年：2010
• 出版时间：May 21, 2010
• 年：2010
• 卷：75
• 期：10
• 页码：3503-3506
• 全文大小：711K
• 年卷期：v.75,no.10(May 21, 2010)
• ISSN：1520-6904

文摘

This paper describes a copper(II) acetate-mediated cyclization−acetoxylation of 6,8-dien-1-ones in the presence of sodium acetate as base. A variety of functionalized cyclopentanes containing synthetic useful allylic alcohol moieties with three contiguous stereogenic centers were synthesized in moderate to good yields with moderate to high regioselectivities.