Biotic鈥揂biotic Interactions: Factors that Influence Peptide鈥揋raphene Interactions

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• 作者：Steve S. Kim ; Zhifeng Kuang ; Yen H. Ngo ; Barry L. Farmer ; Rajesh R. Naik
• 刊名：ACS Applied Materials & Interfaces
• 出版年：2015
• 出版时间：September 16, 2015
• 年：2015
• 卷：7
• 期：36
• 页码：20447-20453
• 全文大小：420K
• ISSN：1944-8252

文摘

Understanding the factors that influence the interaction between biomolecules and abiotic surfaces is of utmost interest in biosensing and biomedical research. Through phage display technology, several peptides have been identified as specific binders to abiotic material surfaces, such as gold, graphene, silver, and so forth. Using graphene鈥損eptide as our model abiotic鈥揵iotic pair, we investigate the effect of graphene quality, number of layers, and the underlying support substrate effect on graphene鈥損eptide interactions using both experiments and computation. Our results indicate that graphene quality plays a significant role in graphene鈥損eptide interactions. The graphene鈥揵iomolecule interaction appears to show no significant dependency on the number of graphene layers or the underlying support substrate.