文摘
The asymmetric intramolecular oxa-Michael reactions of 伪,尾-unsaturated ketones have been achieved by using readily accessible primary鈥搒econdary diamines as the organocatalysts, giving the synthetically useful tetrahydrofurans/2H-pyrans in good yields and with high enantioselectivities (up to 90% ee).
Keywords:
oxa-Michael reaction; organocatalysis; asymmetric catalysis; diamine catalyst; tetrahydrofurans