Experimental Study of the Synergistic Plasticizing Effect of Carbon Dioxide and Ibuprofen on the Glass Transition Temperature of Poly(methyl methacrylate)

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• 作者：Xue-Kun Li ; Hui Lu ; Gui-Ping Cao ; Ying-Hui Qian ; Li-Hua Chen ; Ren-Han Zhang ; Hong-Lai Liu ; Yun-Hai Shi
• 刊名：Industrial & Engineering Chemistry Research
• 出版年：2014
• 出版时间：April 9, 2014
• 年：2014
• 卷：53
• 期：14
• 页码：5873-5885
• 全文大小：556K
• 年卷期：v.53,no.14(April 9, 2014)
• ISSN：1520-5045

文摘

The solubility of small molecules in a polymer and the consequent glass transition temperature reduction of the polymer with a plasticizing effect are two of the most important thermodynamic properties of small molecule鈥損olymer systems. In this study, with an improved dual QCM device and corresponding method for determination, the solubilities of CO₂ in poly(methyl methacrylate) (PMMA) film, ibuprofen (IBU) in supercritical carbon dioxide (SCCO₂), and the CO₂/IBU compound into PMMA film at different temperatures and pressures were determined, respectively, and then the solubility of IBU in PMMA film was calculated according to the theory of infinite dilute solution. Both CO₂ and IBU molecules can plasticize the polymer in CO₂鈥損olymer and drug鈥損olymer systems. For the CO₂鈥揑BU鈥揚MMA ternary system, the glass transition temperature reduction behavior of PMMA versus the pressure of CO₂ and proportion of IBU in PMMA was investigated, which would illustrate the synergistic plasticizing effect of CO₂ and IBU on the glass transition temperature of PMMA.