Myrifabine, the First Dimeric Myrioneuron Alkaloid from Myrioneuron faberi

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• 作者：Ming-Ming Cao ; Sheng-Dian Huang ; Ying-Tong Di ; Chun-Mao Yuan ; Guo-Ying Zuo ; Yu-Cheng Gu ; Yu Zhang ; Xiao-Jiang Hao
• 刊名：Organic Letters
• 出版年：2014
• 出版时间：January 17, 2014
• 年：2014
• 卷：16
• 期：2
• 页码：528-531
• 全文大小：269K
• ISSN：1523-7052

文摘

One Myrioneuron alkaloid, myrifabine (1), the first example of a dimer with 12 chiral centers embraced in a decacyclic novel skeleton, was isolated from Myrioneuron faberi. Its structure was elucidated by spectroscopic data and single-crystal X-ray diffraction. The antimicrobial and cytotoxic activities of 1 were evaluated in vitro.