Total Synthesis of (+)-Fusarisetin A Driven by a One-Pot Four-Reaction Process

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• 作者：Chenguang Liu ; Zhixiong Zeng ; Renzhi Chen ; Xunjin Jiang ; Yinglu Wang ; Yandong Zhang
• 刊名：Organic Letters
• 出版年：2016
• 出版时间：February 5, 2016
• 年：2016
• 卷：18
• 期：3
• 页码：624-627
• 全文大小：368K
• ISSN：1523-7052

文摘

A concise, asymmetric total synthesis of (+)-fusarisetin A, a hybrid natural product, has been achieved. A one-pot four-reaction process efficiently delivered the tetracycle 2 which served as a key intermediate for the synthesis of the title natural product and its analogues through amino acid incorporation.