The pH-Induced Emission Switching and Interesting DNA-Binding Properties of a Novel Dinuclear Ruthenium(II) Complex

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• 作者：Furong Liu ; Kezhi Wang ; Guangyao Bai ; Yongan Zhang ; and Lihua Gao
• 刊名：Inorganic Chemistry
• 出版年：2004
• 出版时间：March 8, 2004
• 年：2004
• 卷：43
• 期：5
• 页码：1799 - 1806
• 全文大小：180K
• 年卷期：v.43,no.5(March 8, 2004)
• ISSN：1520-510X

文摘

A novel dinuclear Ru(II) complex, [(bpy)₂Ru(ebipcH₂)Ru(bpy)₂](ClO₄)₄, where bpy = 2,2'-bipyridine and ebipcH₂ =N-ethyl-4,7-bis([1,10]-phenanthroline[5,6-f]imidazol-2-yl)carbazole, has been newly synthesized. The pH effects onUV-vis absorption and emission spectra of the complex are studied, and ground- and excited-state ionizationconstants of the complex are derived. The binding of the complex to calf thymus (ct) DNA is investigated withabsorption and luminescence titrations, steady-state emission quenching, and viscosity measurements. The complexacts as a pH-induced "on-off" emission switch between pH 8.0 and pH 10.0 with a maximum on-off ratio of ~100which is favorably compared with the other imidazole-containing Ru(II) complex congeners, and a strong ct-DNAintercalator with an intrinsic binding constant of 1.31(±0.08) × 10⁶ M^-1 in buffered 50 mM NaCl.