Temperature-Sensitive Electrochemical Recognition of Tryptophan Enantiomers Based on 尾-Cyclodextrin Self-Assembled on Poly(l-Glutamic Acid)

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• 作者：Yongxin Tao ; Jiangying Dai ; Yong Kong ; Yan Sha
• 刊名：Analytical Chemistry
• 出版年：2014
• 出版时间：March 4, 2014
• 年：2014
• 卷：86
• 期：5
• 页码：2633-2639
• 全文大小：435K
• 年卷期：v.86,no.5(March 4, 2014)
• ISSN：1520-6882

文摘

A poly(l-glutamic acid)/尾-cyclodextrin (P-l-Glu/尾-CD)-modified glassy carbon electrode (GCE) was prepared by electrochemical polymerization of l-glutamic acid on GCE and subsequent self-assembly of 尾-CD onto the obtained P-l-Glu. Electrochemical recognition of tryptophan (Trp) enantiomers with the P-l-Glu/尾-CD was investigated by differential pulse voltammetry (DPV), and the results show that Trp enantiomers can be effectively recognized at the P-l-Glu/尾-CD-modified GCE. It is also interesting to find that temperature plays a crucial role in the enantioselective recognition, which is evidenced by the variable-temperature UV spectra of the inclusion complexes of Trp enantiomers and 尾-CD. Under optimum conditions, the oxidation peak current ratio of l-Trp to d-Trp could reach 2.30, which is attributed to the stereoselectivity of 尾-CD to the enantiomeric pair of Trp.