Polyphenolic Constituents of the Pericarp of Mangosteen (Garcinia mangostana L.)

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• 作者：Morio Yoshimura ; Kana Ninomiya ; Yukari Tagashira ; Kazuhiro Maejima ; Takashi Yoshida ; Yoshiaki Amakura
• 刊名：Journal of Agricultural and Food Chemistry
• 出版年：2015
• 出版时间：September 9, 2015
• 年：2015
• 卷：63
• 期：35
• 页码：7670-7674
• 全文大小：293K
• ISSN：1520-5118

文摘

Three new polyphenols, together with 14 known compounds, were isolated from a hot water extract of mangosteen (Garcinia mangostana L.) pericarp, a plant that has been used medicinally in Southeast Asia. The three new polyphenols were characterized as a 4-aryl-2-flavanylbenzopyran derivative (tentatively named GM-1), 1, 3,4,3鈥?5鈥?tetrahydroxy-5-methoxybenzophenone (GM-2), 2, and 2,3-dihydrochromone derivative (GM-3), 3 on the basis of NMR and MS data. The relative stereostructure of GM-1 was assigned to have 2,3-cis-3,4-trans- and 2鈥?3鈥?cis configurations on the basis of the coupling constants of heterocyclic ring protons in the ¹H NMR spectrum along with nuclear Overhauser effect correlations. The HPLC analysis indicated that major polyphenolic components in the hot water extract of mangosteen pericarp were epicatechin and procyanidin B2 (epicatechin dimer).