Nickel-Catalyzed Redox-Economical Coupling of Alcohols and Alkynes to Form Allylic Alcohols
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- 作者：Kenichiro Nakai ; Yuji Yoshida ; Takuya Kurahashi ; Seijiro Matsubara
- 刊名：Journal of the American Chemical Society
- 出版年：2014
- 出版时间：June 4, 2014
- 年：2014
- 卷：136
- 期：22
- 页码：7797-7800
- 全文大小：283K
- 年卷期：v.136,no.22(June 4, 2014)
- ISSN：1520-5126
文摘
We have developed a redox-economical coupling reaction of alcohols and alkynes to form allylic alcohols under mild conditions. The reaction is redox-neutral as well as redox-economical and thus free from any additives such as a reductant or an oxidant. This atom-economical coupling can be applied for the conversion of both aliphatic and benzylic alcohols to the corresponding substituted allylic alcohols in a single synthetic operation.