Iron-Catalyzed Suzuki−Miyaura Coupling of Alkyl Halides
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- 作者：Takuji Hatakeyama ; Toru Hashimoto ; Yoshiyuki Kondo ; Yuichi Fujiwara ; Hirofumi Seike ; Hikaru Takaya ; Yoshinori Tamada ; Teruo Ono ; Masaharu Nakamura
- 刊名：Journal of the American Chemical Society
- 出版年：2010
- 出版时间：August 11, 2010
- 年：2010
- 卷：132
- 期：31
- 页码：10674-10676
- 全文大小：229K
- 年卷期：v.132,no.31(August 11, 2010)
- ISSN：1520-5126
文摘
In the presence of novel iron(II) chloride−diphosphine complexes and magnesium bromide, lithium arylborates react with primary and secondary alkyl halides to give the corresponding coupling products in good to excellent yields. High functional group compatibility is also demonstrated in the reactions of substrates possessing reactive substituents, such as alkoxycarbonyl, cyano, and carbonyl groups.