Interactions of salt-type minerals with common inorganic flotation depressants were investigatedthrough solution chemistry calculations. From the constructed conditional solubility productlimits and the actual solubility product lines of calcium silicate and phosphate in fluorite, calcite,and apatite single-mineral systems, the critical precipitation pH or concentration of silicate andphosphate in the corresponding mineral suspensions was determined. These values provided afundamental basis for interpreting the results of flotation tests and were in line with the resultsof
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-potential and dispersant adsorption measurements. The surface precipitation of calciumsilicate or phosphate on fluorite and calcite was identified as a major depression mechanism.Selective depressing conditions for different salt-type minerals using Na
2SiO
3 and Na
3PO
4 asdepressants were determined on the basis of solution chemistry calculations of the systems.