Rhodium(III)-catalyzed Oxidative Coupling through C鈥揌 Bond Cleavage Directed by Phosphinoxy Groups

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• 作者：Yuto Unoh ; Yuto Hashimoto ; Daisuke Takeda ; Koji Hirano ; Tetsuya Satoh ; Masahiro Miura
• 刊名：Organic Letters
• 出版年：2013
• 出版时间：July 5, 2013
• 年：2013
• 卷：15
• 期：13
• 页码：3258-3261
• 全文大小：250K
• 年卷期：v.15,no.13(July 5, 2013)
• ISSN：1523-7052

文摘

A straightforward synthesis of phosphaisocoumarins is achieved by the rhodium-catalyzed oxidative coupling of diarylphosphinic and phenylphosphonic acid derivatives with alkynes. The P鈥揙H groups effectively act as the key function for the regioselective C鈥揌 bond cleavage. Related oxidative coupling of phenylphosphine oxides with alkenes can also be conducted smoothly under similar conditions.