Palladium-Catalyzed Decarboxylative Arylation of Benzoylacrylic Acids toward the Synthesis of Chalcones

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• 作者：Yuto Unoh ; Koji Hirano ; Tetsuya Satoh ; Masahiro Miura
• 刊名：The Journal of Organic Chemistry
• 出版年：2013
• 出版时间：May 17, 2013
• 年：2013
• 卷：78
• 期：10
• 页码：5096-5102
• 全文大小：384K
• 年卷期：v.78,no.10(May 17, 2013)
• ISSN：1520-6904

文摘

It has been found that readily available 3-benzoylacrylic acids undergo palladium-catalyzed decarboxylative arylation with arylboronic acids in the presence of a copper salt oxidant to produce chalcone derivatives. The decarboxylative arylation could also be achieved using aryl halides as the alternative aryl source to expand the applicable scope.