Synthesis of Benzo[c]thiophenes by Rhodium(III)-Catalyzed Dehydrogenative Annulation

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• 作者：Keita Fukuzumi ; Yuto Unoh ; Yuji Nishii ; Tetsuya Satoh ; Koji Hirano ; Masahiro Miura
• 刊名：Journal of Organic Chemistry
• 出版年：2016
• 出版时间：March 18, 2016
• 年：2016
• 卷：81
• 期：6
• 页码：2474-2481
• 全文大小：450K
• ISSN：1520-6904

文摘

The dehydrogenative annulation of thiophen-2-carboxamides with 2 equiv of alkynes proceeds efficiently in the presence of a rhodium catalyst and a copper oxidant to furnish multiply substituted benzo[c]thiophenes. Some of the synthesized benzo[c]thiophenes exhibited strong solid-state fluorescence.