文摘
A copper-catalyzed C鈥揌 amidation process, with azides as amino sources under oxidant-free conditions, has been developed. When N-heterocycles were employed as directing groups, sulfonylazide and benzoylazide could be used as amidating reagents to provide corresponding N-arylamides. When amidines or imine were used, tandem C鈥揘/N鈥揘 bond formation occurred to afford indazole derivatives in one pot.