[3 + 2]-Annulation of Prop-2-ynylsulfonium Salts: Access to Hydroindol-5-ones Containing a Methylthio Group

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• 作者：Penghao Jia ; Qinglong Zhang ; Hongxing Jin ; You Huang
• 刊名：Organic Letters
• 出版年：2017
• 出版时间：January 20, 2017
• 年：2017
• 卷：19
• 期：2
• 页码：412-415
• 全文大小：387K
• ISSN：1523-7052

文摘

An unprecedented [3 + 2]-annulation of prop-2-ynylsulfonium salts and p-quinamines was developed, affording a series of hydroindol-5-ones with a methylthio group in moderate to good yields under mild conditions. In this reaction, the prop-2-ynylsulfonium salt acts as a novel C₂ synthon and sulfide does not serve as a leaving group, which provides facile access to organosulfur compouds.