Optimization, Kinetics, and Thermodynamics in the Extraction Process of Puerarin by Decompressing Inner Ebullition

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• 作者：Xiaoguang Chen ; Tengyou Wei ; Mengwei Peng ; Zhangfa Tong
• 刊名：Industrial & Engineering Chemistry Research
• 出版年：2012
• 出版时间：May 16, 2012
• 年：2012
• 卷：51
• 期：19
• 页码：6841-6846
• 全文大小：264K
• 年卷期：v.51,no.19(May 16, 2012)
• ISSN：1520-5045

文摘

Decompressing inner ebullition (DIE) is a novel method and it can achieve a rapid extraction at lower temperature for active constituents of medical plants. In this work, DIE was employed to extract puerarin from puerarin lobata (Willd.) Ohwi (PLO). The extraction conditions were investigated according single factor analysis. Experiment results showed that the extraction yield of puerarin reached a maximum value when the ethanol mass concentration in the aqueous solution immersing the PLO was 60%, the amount of ethanol solution for premaceration and of water for extraction were 1.6 and 10 mL路g^鈥? of PLO, respectively, the operation gauge pressure was 鈭?.084 MPa, and the extraction temperature was 50 掳C. Under the optimal conditions, the extraction kinetics of DIE was studied. The mass transfer coefficient of DIE ranged between 0.09 and 0.13 s^鈥?, which is 183 times greater than that of ultrasonic assistant extraction under the same conditions, and its extraction activation energy 螖E is 10.86 kJ路mol^鈥?. Also, the thermodynamics properties in the extraction process of DIE at 50 掳C were also calculated, the enthalpy change 螖H is 58.76 kJ路mol^鈥?, the entropy change 螖S is 224.50 J路mol^鈥?路K^鈥?, and Gibbs free energy 螖G is 鈭?3.73 kJ路mol^鈥?, respectively. The extraction of DIE belongs to a spontaneous process with endothermic and entropy increasing.