Autoxidative C(sp2)–P Formation: Direct Phosphorylation of Heteroarenes under Oxygen, Metal-Free, and Solvent-Free Conditions
详细信息 查看全文
- 作者：Kai Luo ; Yao-Zhong Chen ; Li-Xian Chen ; Lei Wu
- 刊名：Journal of Organic Chemistry
- 出版年：2016
- 出版时间：June 3, 2016
- 年：2016
- 卷：81
- 期：11
- 页码：4682-4689
- 全文大小：483K
- 年卷期：0
- ISSN：1520-6904
文摘
We reveal here a direct autoxidative phosphorylation of heteroarenes induced by oxygen under metal-free and solvent-free conditions. This new methodology provides an economical, operationally simple, and environmentally friendly approach toward (Het)C(sp2)–P formation with medium to excellent yields. Heteroarenes including thiazole and quinoxaline derivatives are applicable under standard conditions, which is testified via a radical mechanism.