Ruthenium(II)-Catalyzed C鈥揌 Arylation of Azoarenes by Carboxylate Assistance

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• 作者：Jonathan Hubrich ; Thomas Himmler ; Lars Rodefeld ; Lutz Ackermann
• 刊名：ACS Catalysis
• 出版年：2015
• 出版时间：July 2, 2015
• 年：2015
• 卷：5
• 期：7
• 页码：4089-4093
• 全文大小：387K
• ISSN：2155-5435

文摘

Ruthenium(II)carboxylate complexes enabled the unprecedented direct C鈥揌 arylation of azoarenes with aryl halides through chelation assistance. The mild reaction conditions of the optimized C鈥揌 functionalization process resulted in a remarkable functional group tolerance. The proximity-induced C鈥揌 arylation proceeded with high positional selectivity and could be performed in a one-pot protocol along with a azoarene reduction, providing expedient access to ortho-arylated anilines.