Palladium-Catalyzed C−H Functionalization of Heteroarenes with Aryl Bromides and Chlorides

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• 作者：Shunsuke Tamba ; Youhei Okubo ; Shota Tanaka ; Daiki Monguchi ; Atsunori Mori
• 刊名：Journal of Organic Chemistry
• 出版年：2010
• 出版时间：October 15, 2010
• 年：2010
• 卷：75
• 期：20
• 页码：6998-7001
• 全文大小：717K
• 年卷期：v.75,no.20(October 15, 2010)
• ISSN：1520-6904

文摘

Palladium-catalyzed C−H arylation of electron-enriched heteroarenes with aryl bromides and aryl chlorides proceeds in the presence of LiO-t-Bu as a base. The reaction allows one-pot synthesis of differently substituted 2,5-diarylthiazole with the same catalyst system by switching the solvent and the amount of base.