Gold-Catalyzed Intramolecular Cyclization of N-Propargylic 尾-Enaminones for the Synthesis of 1,4-Oxazepine Derivatives

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• 作者：Kommuru Goutham ; Desamala Ashok Kumar ; Surisetti Suresh ; Balasubramanian Sridhar ; Ravirala Narender ; Galla V. Karunakar
• 刊名：Journal of Organic Chemistry
• 出版年：2015
• 出版时间：November 6, 2015
• 年：2015
• 卷：80
• 期：21
• 页码：11162-11168
• 全文大小：448K
• ISSN：1520-6904

文摘

An efficient and mild one-pot, gold-catalyzed intramolecular cyclization of N-propargylic 尾-enaminones has been achieved for the generation of 1,4-oxazepine derivatives. This synthetic transformation tolerates a range of substituted N-propargylic 尾-enaminones in moderate to good yields.