Spatial Analysis of Potential Carcinogenic Risks Associated with Ingesting Arsenic in Aquacultural Tilapia (Oreochromis mossambicus) in Blackfoot Disease Hyperendemic Areas

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• 作者：Cheng-Shin Jang ; Chen-Wuing Liu ; Kao-Hung Lin ; Feng-Mei Huang ; and Sheng-Wei Wang
• 刊名：Environmental Science & Technology
• 出版年：2006
• 出版时间：March 1, 2006
• 年：2006
• 卷：40
• 期：5
• 页码：1707 - 1713
• 全文大小：379K
• 年卷期：v.40,no.5(March 1, 2006)
• ISSN：1520-5851

文摘

This work analyzed spatially potential carcinogenic risksassociated with ingesting arsenic (As) contents in aquaculturaltilapia (Oreochromis mossambicus) in coastal regions ofsouthwestern Taiwan, where the blackfoot disease prevails.Sequential indicator simulation (SIS) was used toreproduce As exposure distributions in groundwaterbased on their three-dimensional variability. A target cancerrisk (TR) associated with ingesting As in aquaculturaltilapia was calculated to evaluate the potential risk to humanhealth. Owing to sparse measured data, Monte Carlosimulation and SIS properly accounted for the uncertaintyof assessed parameters. The probabilistic risk assessmentformulated suitable strategies under various remedial stages.Aquacultural regions with high risks were mapped toelucidate the safety of groundwater use at different depths.Many TRs determined from the risks at the 75th and95th percentiles exceed one millionth in the regions,indicating that ingesting tilapia farmed in the highly As-polluted regions poses potential cancer threats to humanhealth. The 75th percentile of TR is considered informulating a remedial strategy for the aquacultural useof groundwater in the preliminary stage. Additionally, thisstudy suggests reducing the use of groundwater inaquaculture or changing the depths from which groundwateris withdrawn in the areas with high risks of cancer.