Copper and Silver Complexes of Tris(triazole)amine and Tris(benzimidazole)amine Ligands: Evidence that Catalysis of an Azide鈥揂lkyne Cycloaddition (鈥淐lick鈥? Reaction by a Silver Tris(triazole)amine Com
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- 作者：Timothy U. Connell ; Christine Schieber ; Ilaria Proietti Silvestri ; Jonathan M. White ; Spencer J. Williams ; Paul S. Donnelly
- 刊名：Inorganic Chemistry
- 出版年：2014
- 出版时间：July 7, 2014
- 年：2014
- 卷：53
- 期：13
- 页码：6503-6511
- 全文大小：406K
- ISSN：1520-510X
文摘
The synthesis and characterization of a silver complex of the tripodal triazole ligand, tris(benzyltriazolylmethyl)amine (TBTA, L1), that is used as promoter to enhance CuI-catalyzed azide鈥揳lkyne cycloaddition (CuAAC) reactions is reported. X-ray analysis of the silver(I) complex with L1 reveals a dinuclear cation, [Ag2(L1)2]2+, that is essentially isostructural to the copper(I) analogue. While the [Ag2(L1)2](BF4)2 complex provides catalysis for the azide鈥揳lkyne cycloaddition process, evidence is presented that this arises from trace copper contamination. The synthesis of silver(I), copper(II), and copper(I) complexes of a second tripodal ligand, tris(2-benzimidazolymethyl)amine (L2), which is used to enhance the rate of CuAAC reactions, is also reported. X-ray crystallography of the CuI complex [CuI3(L2)2(CH3CN)2](BF4)3 offers structural insight into previous mechanistic speculation about the role of this ligand in the CuAAC reaction.