Separation and Purification of (鈭?-Shikimic Acid and (鈭?-Quinic Acid by the Phase Diagrams of the Ternary System of (鈭?-Shikimic Acid + (鈭?-Quinic Acid + H2O and the Quaternary System of (鈭

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• 作者：Xinying Hao ; Qiang Huang ; Guopeng Shen ; Xiaoru Wu ; Guoqin Hu ; Chunlan Ban
• 刊名：Industrial & Engineering Chemistry Research
• 出版年：2015
• 出版时间：July 15, 2015
• 年：2015
• 卷：54
• 期：27
• 页码：6993-6998
• 全文大小：293K
• ISSN：1520-5045

文摘

The solid鈥搇iquid phase equilibrium for the ternary system of (鈭?-Shikimic acid + (鈭?-Quinic acid + H₂O and the quaternary system of (鈭?-Shikimic acid + (鈭?-Quinic acid + Ethanol (蠁 鈭?50%,蠁 鈭?75%) + H₂O was measured at T = 298.15, 318.15, 333.15, 348.15 K, and mutual solubility was obtained. Three variable-temperature phase diagrams were constructed according to the experimental solubility. In the phase diagrams, there were in all one invariant point, two univariant curves, and two crystallization regions corresponding to (鈭?-Shikimic acid and (鈭?-Quinic acid at each temperature in the studied system. The crystallization regions of the pure two solids increase with a decrease in temperature. The variable-temperature diagrams for the quaternary system of (鈭?-Shikimic acid + (鈭?-Quinic acid + Ethanol (蠁 鈭?50%) + H₂O can be used for effective separation and purification of (鈭?-Shikimic acid and (鈭?-Quinic acid. Meanwhile, the solid + liquid phase equilibrium data can be used for the separation process of (鈭?-Shikimic acid and (鈭?-Quinic acid in industrial production and further theoretical studies.