Gneyulins A and B, Stilbene Trimers, and Noidesols A and B, Dihydroflavonol-C-Glucosides, from the Bark of Gnetum gnemonoides

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• 作者：Yoko Shimokawa ; Yusuke Akao ; Yusuke Hirasawa ; Khalijah Awang ; A. Hamid A. Hadi ; Seizo Sato ; Chihiro Aoyama ; Jiro Takeo ; Motoo Shiro ; Hiroshi Morita
• 刊名：Journal of Natural Products
• 出版年：2010
• 出版时间：April 23, 2010
• 年：2010
• 卷：73
• 期：4
• 页码：763-767
• 全文大小：209K
• 年卷期：v.73,no.4(April 23, 2010)
• ISSN：1520-6025

文摘

Gneyulins A (1) and B (2), two new stilbene trimers consisting of oxyresveratrol constituent units, and noidesols A (3) and B (4), two new dihydroflavonol-C-glucosides, were isolated from the bark of Gnetum gnemonoides. The structures and configurations of 1−4 were elucidated on the basis of 2D NMR correlations and X-ray analysis. Gneyulins A (1) and B (2) showed inhibition of Na⁺-glucose transporters (SGLT-1 and SGLT-2).