Synthesis, Characterization, and Bioconjugation of Fluorescent Gold Nanoclusters toward Biological Labeling Applications

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• 作者：Cheng-An J. Lin ; Ting-Ya Yang ; Chih-Hsien Lee ; Sherry H. Huang ; Ralph A. Sperling ; Marco Zanella ; Jimmy K. Li ; Ji-Lin Shen ; Hsueh-Hsiao Wang ; Hung-I Yeh ; Wolfgang J. Parak ; Walter H. Chang
• 刊名：ACS Nano
• 出版年：2009
• 出版时间：February 24, 2009
• 年：2009
• 卷：3
• 期：2
• 页码：395-401
• 全文大小：449K
• 年卷期：0
• ISSN：1936-086X

文摘

Synthesis of ultrasmall water-soluble fluorescent gold nanoclusters is reported. The clusters have a decent quantum yield, high colloidal stability, and can be readily conjugated with biological molecules. Specific staining of cells and nonspecific uptake by living cells is demonstrated.