Rapid Identification of Bacteria with a Disposable Colorimetric Sensing Array

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• 作者：James R. Carey ; Kenneth S. Suslick ; Keren I. Hulkower ; James A. Imlay ; Karin R. C. Imlay ; Crystal K. Ingison ; Jennifer B. Ponder ; Avijit Sen ; Aaron E. Wittrig
• 刊名：Journal of the American Chemical Society
• 出版年：2011
• 出版时间：May 18, 2011
• 年：2011
• 卷：133
• 期：19
• 页码：7571-7576
• 全文大小：932K
• 年卷期：v.133,no.19(May 18, 2011)
• ISSN：1520-5126

文摘

Rapid identification of both species and even specific strains of human pathogenic bacteria grown on standard agar has been achieved from the volatiles they produce using a disposable colorimetric sensor array in a Petri dish imaged with an inexpensive scanner. All 10 strains of bacteria tested, including Enterococcus faecalis and Staphylococcus aureus and their antibiotic-resistant forms, were identified with 98.8% accuracy within 10 h, a clinically important time frame. Furthermore, the colorimetric sensor arrays also proved useful as a simple research tool for the study of bacterial metabolism and as an easy method for the optimization of bacterial production of fine chemicals or other fermentation processes.