Bromine Radical-Mediated Sequential Radical Rearrangement and Addition Reaction of Alkylidenecyclopropanes

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• 作者：Takashi Kippo ; Kanako Hamaoka ; Ilhyong Ryu
• 刊名：The Journal of the American Chemical Society
• 出版年：2013
• 出版时间：January 16, 2013
• 年：2013
• 卷：135
• 期：2
• 页码：632-635
• 全文大小：275K
• 年卷期：v.135,no.2(January 16, 2013)
• ISSN：1520-5126

文摘

Bromine radical-mediated cyclopropylcarbinyl-homoallyl rearrangement of alkylidenecyclopropanes was effectively accomplished by C鈥揅 bond formation with allylic bromides, which led to the syntheses of 2-bromo-1,6-dienes. A three-component coupling reaction comprising alkylidenecyclopropanes, allylic bromides, and carbon monoxide also proceeded well to give 2-bromo-1,7-dien-5-ones in good yield.