α-Arylation of 3-Aryloxindoles
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- 作者：Cheng-Kang Mai ; Matthew F. Sammons ; Tarek Sammakia
- 刊名：Organic Letters
- 出版年：2010
- 出版时间：May 21, 2010
- 年：2010
- 卷：12
- 期：10
- 页码：2306-2309
- 全文大小：205K
- 年卷期：v.12,no.10(May 21, 2010)
- ISSN：1523-7052
文摘
A versatile method for the synthesis of 3,3-diaryloxindoles via Pd-catalyzed α-arylations or an SNAr reaction is described. The reaction proceeds using mild base, is tolerant of a variety of functional groups, and is capable of preparing hindered all-carbon quaternary centers.