Unexpected Formation of Aryl Ketones by Palladium-Catalyzed Coupling of Aryl Bromides with Vinylic Acetates

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• 作者：Micka&euml ; l Jean ; Jacques Renault ; Philippe Uriac ; Marc Capet ; Pierre van de Weghe
• 刊名：Organic Letters
• 出版年：2007
• 出版时间：August 30, 2007
• 年：2007
• 卷：9
• 期：18
• 页码：3623 - 3625
• 全文大小：69K
• 年卷期：v.9,no.18(August 30, 2007)
• ISSN：1523-7052

文摘

A palladium-catalyzed coupling reaction of aryl bromides with vinylic acetates in the presence of tributyltin methoxide has been described.Unexpected formation of aryl ketones was obtained. Preliminary mechanistic studies indicated that the reaction proceeded by the addition ofthe aryl moiety in the coordination sphere of palladium to a ketene.