Molecular Light Switches for Calf Thymus DNA Based on Three Ru(II) Bipyridyl Complexes with Variations of Heteroatoms
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- 作者：Mei-Jiao Han ; Zhi-Ming Duan ; Qiang Hao ; Shuai-Zhi Zheng ; Ke-Zhi Wang
- 刊名：Journal of Physical Chemistry C
- 出版年：2007
- 出版时间：November 8, 2007
- 年：2007
- 卷：111
- 期：44
- 页码：16577 - 16585
- 全文大小：154K
- 年卷期：v.111,no.44(November 8, 2007)
- ISSN：1932-7455
文摘
The three Ru(II) complexes of [Ru(bpy)2(bipp)](ClO4)2 (1), [Ru(bpy)2(bopp)](ClO4)2 (2), and [Ru(bpy)2(btpp)](ClO4)2 (3) (where bpy = 2,2'-bipyridine, bipp = 2-benzimidazoyl-pyrazino[2,3-f] [1,10]phenanthroline,bopp = 2-benzoxazolyl-pyrazino[2,3-f] [1,10]phenanthroline, and btpp = 2-benzthiazolyl-pyrazino[2,3-f] [1,10]phenanthroline) with variations in heteroatoms of NH (1), O(2), and S(3), have been synthesized andcharacterized. These complexes have been shown to act as promising calf thymus DNA intercalators and anew class of DNA light switches for the DNA, as evidenced by UV-visible and luminescence titrations,steady-state emission quenching by [Fe(CN)6]4-, DNA competitive binding with ethidium bromide, reversesalt titrations, viscosity measurements, and DNA melting experiments.