Sodium Tetramethoxyborate: An Efficient Catalyst for Michael Additions of Stabilized Carbon Nucleophiles

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• 作者：Araceli G. Campañ ; a ; Noelia Fuentes ; Enrique G&oacute ; mez-Bengoa ; Cristina Mateo ; J. Enrique Oltra ; Antonio M. Echavarren ; Juan M. Cuerva
• 刊名：Journal of Organic Chemistry
• 出版年：2007
• 出版时间：October 12, 2007
• 年：2007
• 卷：72
• 期：21
• 页码：8127 - 8130
• 全文大小：83K
• 年卷期：v.72,no.21(October 12, 2007)
• ISSN：1520-6904

文摘

jo701354cn00001>Sodium tetramethoxyborate, easily prepared by reaction ofinexpensive sodium borohydride with methanol, possessesa suitable combination of a Lewis base and a Lewis acid tocatalyze Michael reactions at room temperature underpractically neutral conditions. This reaction provides goodto excellent yields of Michael addition products from a broadscope of Michael donor and Michael acceptor reagents.