Design, Synthesis, Bioactivity, and Structure−Activity Relationship (SAR) Studies of Novel Benzoylphenylureas Containing Oxime Ether Group

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• 作者：Ranfeng Sun ; Maoyun L ; Li Chen ; Qingshan Li ; Haibin Song ; Fuchun Bi ; Runqiu Huang ; Qingmin Wang
• 刊名：Journal of Agricultural and Food Chemistry
• 出版年：2008
• 出版时间：December 10, 2008
• 年：2008
• 卷：56
• 期：23
• 页码：11376-11391
• 全文大小：621K
• 年卷期：v.56,no.23(December 10, 2008)
• ISSN：1520-5118

文摘

Novel benzoylphenylureas containing an oxime ether group were designed and synthesized by four schemes. These benzoylphenylureas were identified by ¹H NMR spectroscopy and element analysis (or HRMS). The bioactivities of the new compounds were evaluated. These benzoylphenylureas exhibited excellent larvicidal activities against oriental armyworm, some of which were much better in comparison with the commercial Flucycloxuron. In particular, the larvicidal activities against oriental armyworm of compounds 1 and 23 were 5−10 times better than that of Flucycloxuron. Most of these benzoylphenyureas exhibited excellent larvicidal activities against mosquito. At the same time, some of these compounds have good plant growth regulatory activities as well.