Peptoids and Polypeptoids at the Frontier of Supra- and Macromolecular Engineering
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- 作者：Niklas Gangloff ; Juliane Ulbricht ; Thomas Lorson ; Helmut Schlaad ; Robert Luxenhofer
- 刊名：Chemical Reviews
- 出版年：2016
- 出版时间：February 24, 2016
- 年：2016
- 卷：116
- 期：4
- 页码：1753-1802
- 全文大小：2812K
- 年卷期：Niklas Gangloff (pictured 2nd from left) received his B.Sc. in Chemistry from the Technical University (TU) of Dresden while conducting cell viability studies of different cell lines when incubated with an anticancer drug. In the course of his Master’s studies, he worked on biodegradable nanogel star polymers at the IBM Almaden Research Center in San José, California, and received his M.Sc. from the TU developing the solid-phase peptoid polymerization (SP3). Since 2013, he has been working on his Ph.D. at the University of Würzburg. In collaboration with Ronald Zuckermann at the Lawrence Berkeley National Laboratory, he is investigating polypeptoids and their aggregation behavior.Juliane Ulbricht (pictured 3rd from left) studied chemistry at the TU Dresden, Germany, and received her MSc. in 2013 for her Master’s thesis on the oxidative degradation of pseudopolypeptides. In 2014, she joined the group of Robert Luxenhofer at Würzburg University as a Ph.D. student. Her current research interests include the degradation behavior of polypeptoids by oxidative species as well as enzymes.Thomas Lorson (pictured far right) received his B.Sc. and M.Sc. in Functional Materials from the Julius-Maximilians-University in Würzburg, Germany. Under the guidance of Prof. Gerhard Sextl, he completed his thesis at the Fraunhofer ISC in developing preceramic polymers for the production of fibers. He joined the group of Robert Luxenhofer as a Ph.D. candidate in 2014. His current research focuses on the development of novel polymeric biomaterials and scaffold designs for tissue engineering applications.Helmut Schlaad studied chemistry at the University of Mainz, Germany, and earned a doctoral degree in Physical Chemistry, under Axel H. E. Müller in 1997. After one year of postdoctoral fellowship with Rudolf Faust at the University of Massachusetts in Lowell, USA, he moved to the Max Planck Institute of Colloids and Interfaces in Potsdam, Germany. He finished habilitation, mentored by Prof. Markus Antonietti, and received the venia legendi in Physical Chemistry in 2004. He was senior scientist at the Max Planck Institute of Colloids and Interfaces until 2014 and then moved to the University of Potsdam as a professor for polymer chemistry. His research interests are directed toward polymer synthesis, smart functional materials, and bioinspired polymer structures.Robert Luxenhofer (pictured left) studied chemistry at the TU München, Germany, and Sydney University, Australia. In 2007, he received his Ph.D. in polymer chemistry under the supervision of Rainer Jordan. Under the guidance of Alexander (Sasha) Kabanov, he conducted postdoctoral research in the field of nanomedicine and drug delivery at the University of Nebraska Medical Center in Omaha, Nebraska. In 2009, he returned to Germany as a KAUST Research Fellow and started to work on polypeptoids at the TU Dresden. Since 2012, he has been a professor for functional polymer materials at the Julius-Maximilians University Würzburg. His research interests include polypeptoids and poly(2-oxazoline)s, multicomponent reactions, nanomedicine and regenerative medicine, interaction of polymers with biological systems, and the questions of what we define as reproducibility in polymer science.
- ISSN：1520-6890
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