文摘
In a continuing search for novel bioactive compounds from marine mangrove plants, seven new naphthoquinone derivativeswere isolated from Avicennia marina, namely, avicennone A (1), avicennone B (2), avicennone C (3), avicennone D(4), avicenone E (5), avicennone F (6), and avicennone G (7), along with the known compounds avicequinone A (8),stenocarpoquinone B (9), avicequinone C (10), avicenol A (11), and avicenol C (12). The chemical structures of 1-7were elucidated by spectroscopic methods. Compounds 8-10, and a mixture of 4 and 5, which all contain a 4,9-dionegroup, showed strong antiproliferative and moderate cytotoxic activities, as well as antibacterial effects.