Metal–Organic Framework Nodes Support Single-Site Magnesium–Alkyl Catalysts for Hydroboration and Hydroamination Reactions

详细信息    查看全文

• 作者：Kuntal Manna ; Pengfei Ji ; Francis X. Greene ; Wenbin Lin
• 刊名：Journal of the American Chemical Society
• 出版年：2016
• 出版时间：June 22, 2016
• 年：2016
• 卷：138
• 期：24
• 页码：7488-7491
• 全文大小：376K
• 年卷期：0
• ISSN：1520-5126

文摘

Here we present the first example of a single-site main group catalyst stabilized by a metal–organic framework (MOF) for organic transformations. The straightforward metalation of the secondary building units of a Zr-MOF with Me₂Mg affords a highly active and reusable solid catalyst for hydroboration of carbonyls and imines and for hydroamination of aminopentenes. Impressively, the Mg-functionalized MOF displayed very high turnover numbers of up to 8.4 × 10⁴ for ketone hydroboration and could be reused more than 10 times. MOFs can thus be used to develop novel main group solid catalysts for sustainable chemical synthesis.