Electrophoretic Transport of Biomolecules through Carbon Nanotube Membranes

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• 作者：Xinghua Sun ; Xin Su ; Ji Wu ; Bruce J. Hinds
• 刊名：Langmuir
• 出版年：2011
• 出版时间：March 15, 2011
• 年：2011
• 卷：27
• 期：6
• 页码：3150-3156
• 全文大小：821K
• 年卷期：v.27,no.6(March 15, 2011)
• ISSN：1520-5827

文摘

Electrophoretic transport of proteins across electrochemically oxidized multi-walled carbon nanotube (MWCNT) membranes has been investigated. A small charged protein, lysozyme, was successfully pumped across MWCNT membranes by an electric field while rejecting larger bovine serum albumin (BSA). Transport of lysozome was reduced by a factor of about 30 in comparison to bulk mobility and consistent with the prediction for hindered transport. Mobilities between 0.33 and 1.4 脳 10^鈭? m² V^鈭? s^鈭? were observed and are approximately 10-fold faster than comparable ordered nanoporous membranes and consistent with continuum models. For mixtures of BSA and lysozyme, complete rejection of BSA is seen with electrophoretic separations.