Effects of Chinese Medicine Shen-Fu Injection (参附注射洿 on the expression of inflammatory cytokines and complements during post-resuscitation immune dysfunction in a porcine model

详细信息    查看全文

• 作者：Qian Zhang 庿芿/a> ; Chun-sheng Li 李春癿/a> ; Shuo Wang 猿灿/a>…
• 关键词：cardiac arrest ; complement activation ; cytokines ; immune dysfunction
• 刊名：Chinese Journal of Integrative Medicine
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：22
• 期：2
• 页码：101-109
• 全文大小：1,102 KB
• 参考文献：1.Nichol G, Thomas E, Callaway CW, Hedges J, Powell JL, Aufderheide TP, et al. Regional variation in out-of-hospital cardiac arrest incidence and outcome. JAMA 2008; 300;1423–1431.PubMedCentral CrossRef PubMed
  2.Adrie C, Adib-Conquy M, Laurent I. Successful cardiopulmonary resuscitation after cardiac arrest as a “sepsis-like” syndrome. Circulation 2002;106:562–568.CrossRef PubMed
  3.Suzuki H, Lasbury ME, Fan L, Vittal R, Mickler EA, Benson HL, et al. Role of complement activation in obliterative bronchiolitis post-lung transplantation. J Immunol 2013;191:4431–4439.CrossRef PubMed
  4.Zhang C, Li Y, Wang C, Wu Y, Cui W, Miwa T, et al. Complement 5a receptor mediates angiotensin II-induced cardiac inflammation and remodeling. Arterioscler Thromb Vasc Biol 2014;34:1240–1248.CrossRef PubMed
  5.Frey A, Ertl G, Angermann CE, Hofmann U, Störk S, Frantz S. Complement C3c as a biomarker in heart failure. Mediators Inflamm 2013;2013:716902.PubMedCentral CrossRef PubMed
  6.Bottiger BW, Motsch J, Braun V. Marked activation of complement and leukocytes and an increase in the concentrations of soluble endothelial adhesion molecules during cardiopulmonary resuscitation and early reperfusion after cardiac arrest in humans. Crit Care Med 2002;30:2473–2480.CrossRef PubMed
  7.Callaway CW, Rittenberger JC, Logue ES. Hypothermia after cardiac arrest does not alter serum inflammatory markers. Crit Care Med 2008;36:2607–2612.CrossRef PubMed
  8.Fries M, Stoppe C, Brucken D. Influence of mild therapeutic hypothermia on the inflammatory response after successful resuscitation from cardiac arrest. J Crit Care 2009;24:453–457.CrossRef PubMed
  9.Zhang Q, Li C. The roles of traditional Chinese medicine: Shen-Fu Injection on the postresuscitation care bundle. Evid Based Complem Altern Med 2013;2013:319092.
  10.Hou XM, Li CS, Gu W, Guo ZJ, Yin WP, Zhang D. Effect of Shenfu on inflammatory cytokine release and brain edema after prolonged cardiac arrest in the swine. Am J Emerg Med 2013;31:1159–1164.CrossRef PubMed
  11.Ji XF, Yang L, Li CS. Shen-Fu injection attenuates postresusbitation myocardial dysfunction in a porcine model of cardiac arrest. Shock 2011;35:530–536.CrossRef PubMed
  12.Gu W, Li CS, Yin WP. Shen-Fu injection reduces postresuscitation myocardial dysfunction in a porcine model of cardiac arrest by modulating apoptosis. Shock 2012;38:301–306.CrossRef PubMed
  13.Zhu J, Kang L, Ye Q, Fan G, Liang Y. Effects of Shenfu Injection and its main components on the contraction of isolated rat thoracic aortic rings. PLoS ONE 2013;8:e78026.PubMedCentral CrossRef PubMed
  14.Huang Q, Xu H, Yu Z, Gao P, Liu S. Inbred Chinese wuzhishan (wzs) minipig model for soybean glycinin and beta-conglycinin allergy. J Agric Food Chem 2010;58:5194–5198.CrossRef PubMed
  15.Wang S, Li CS, Ji XF. Effect of continuous compressions and 30:2 cardiopulmonary resuscitation on global ventilation/perfusion values during resuscitation in a porcine model. Crit Care Med 2010;38:2024–2030.PubMed
  16.Valenzuela TD, Roe DJ, Cretin S. Estimating effectiveness of cardiac arrest interventions. Circulation 1997;96:3308–3313.CrossRef PubMed
  17.Ji XF, Li CS, Wang S. Comparison of the efficacy of nifekalant and amiodarone in a porcine model of cardiac arrest. Resuscitation 2010;81:1031–1036.CrossRef PubMed
  18.Meybohm P, Gruenewald M, Zacharowski KD. Mild hypothermia alone or in combination with anesthetic post-conditioning reduces expression of inflammatory cytokines in the cerebral cortex of pigs after cardiopulmonary resuscitation. Crit Care 2010;14–21.
  19.Gu W, Li CS, Yin WP, Hou XM, Zhang D. Effects of Shen-Fu Injection on the expression of T-cell-specific transcription factors t-bet/Gata-3 in porcine Postresuscitation lung injury. Evid Based Complem Altern Med 2013;2013:464650.
  20.Patrick M, Matthias G, Martin A. Hypothermia and postconditioning after cardiopulmonary resuscitation reduce cardiac dysfunction by modulating inflammation, apoptosis and remodeling. PLoS One 2009;4:e7588.CrossRef
  21.Niemann JT, Garner D, Lewis RJ. Tumor necrosis factor-α is associated with early postresuscitation myocardial dysfunction. Crit Care Med 2004;32:175–1758.CrossRef
  22.Geppert A, Zorn G, Karth GD, Haumer M, Gwechenberger M. Soluble selectins and the systemic inflammatory response syndrome after successful cardiopulmonary resuscitation. Crit Care Med 2000;28:2360–2365.CrossRef PubMed
  23.Sairanen T, Carpen O, Karjalainen-Lindsberg M. Evolution of cerebral tumor necrosis factor-α production during human ischemic stroke. Stroke 2001;32:1750–1758.CrossRef PubMed
  24.Lucchesi BR, Tanhehco EJ. Therapeutic potential of complement inhibitors in myocardial ischaemia. Expert Opin Invest Drugs 2000;9:975–991.CrossRef
  25.Müller-Eberhard HJ. Molecular organization and function of the complement system. Annu Rev Biochem 1988;57:321–347.CrossRef PubMed
  26.Kirschfink M. Controlling the complement system in inflammation. Immunopharmacology 1997;38:51–62.CrossRef PubMed
  27.Hattori R, Hamilton KK, McEver RP. Complement protein C5b-9 induces secretion of high molecular weight multimers of endothelial von Willebrand factor and translocation of granule membrane protein GMP-140 to the cell surface. J Biol Chem 1989;264:9053–9060.PubMed
  28.Crawford MH, Grover FL, Kolb WP. Complement and neutrophil activation in the pathogenesis of ischemic myocardial injury. Circulation 1988;78:1449–1458.CrossRef PubMed
  29.Homeister JW, Satoh P, Lucchesi BR. Effects of complement activation in the isolated heart: role of the terminal complement components. Circ Res 1992;71:303–319.CrossRef PubMed
  30.Zhang MY, Ji XF, Wang S, Li CS. Shen-Fu injection attenuates postresuscitation lung injury in a porcine model of cardiac arrest. Resusciatation 2012;83:1152–1158.CrossRef
  31.Zhang XJ, Song L, Zhou ZG, Wang XM. Effect of Shenfu injection on gastrointestinal microcirculation in rabbits after myocardial ischemia-reperfusion injury. World J Gastroenterol 2006;12:4389–4391.PubMedCentral PubMed
  32.Zheng CD, Min S. Cardioprotection of Shenfu Injection against myocardial ischemia/reperfusion injury in open heart surgery. Chin J Integr Med 2008;14:10–16.CrossRef PubMed
  33.Cao J, Zheng CD, Zhang GX, Zhang YJ, Min S. Protective effect of Shenfu injection on myocardial mitochondria injured by ischemia-reperfusion in rabbits. Chin Med J 2005;118:505–507.PubMed
  34.Xie J, Weil MH, Sun S. High-energy defibrillation increases the severity of postresuscitation myocardial dysfunction. Circulation 1997;96:683–688.CrossRef PubMed
  
• 作者单位：Qian Zhang 张 茜 (1)
  Chun-sheng Li 李春盛 (1)
  Shuo Wang 王 烁 (1)
  Wei Gu 顾 伟 (1)
  
  1. Department of Emergency Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing, 100020, China
  
• 刊物主题：Medicine/Public Health, general;
• 出版者：Springer Berlin Heidelberg
• ISSN：1993-0402

文摘

Objective To investigate the action of Shen-Fu Injection (参附注射液, SFI) in regulating the expression of the serum complements and inflammatory cytokines synthesized and released in response to the stress of global ischemia accompanying cardiac arrest (CA) and resuscitation.